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All species of ''[[Brettanomyces]]'' can produce forms of tetrahydropyridine in varying amounts, although some below threshold. Additionally, Lactic Acid Bacteria (LAB) including ''[[Lactobacillus]]'' and ''[[Pediococcus]]'' can produce forms of THP. Acetic Acid Bactera (AAB) has also been demonstrated to produce forms of THP <ref name="Snowdon"></ref><ref name="Grbin_2000" />.
Moulis et al. (2023) studied THP production by 22 strains of ''Brettanomyces bruxellensis'', 20 strains of ''Oenococcus oeni'' and 10 strains of ''Lentilactobacillus hilgardii'' (formerly classified as ''Lactobacillus hilgardii''), all of which have been reported to produce THP compounds. They found that all strains could produce ATHP, but not all strains could produce ETHP or APY. This variability was determined mostly by species, but also by strain. for example, all of the 22 ''B. bruxellensis'' strains only produced ATHP and ETHP and not APY. Variability between strains was less pronounced for the species ''L. hilgardii'' compared to the ''B. bruxellensis'' and ''O. oeni'' strains (different strains of ''B. bruxellensis'', for example, produced much different levels of ATHP/ETHP, where as every strain of ''L. hilgardii'' produced relatively the same amount of APY). The researchers also noted that repeatability of THP levels was difficult to achieve, and they owed this to unknown variables such as the physiological state of the cells at time of inoculation into the test media. Interestingly, there was no correlation between strain genealogy and how much THP they produced. They also reported that for organisms that produced ETHP, there was always a 1:10 ratio between ETHP/ATHP or ETHP/APY, suggesting that there might be governed by the chemistry of the media used and/or the [https://en.wikipedia.org/wiki/Reduction_potential reduction potential] <ref name="Moulis_2023" />.
===''Brettanomyces''===